Department of Clinical Physiology, Nuclear Medicine and PET
PET 3982
Rigshopitalet (Copenhagen University Hospital)
Blegdamsvej 9
DK-2100 Copenhagen
Denmark
I am currently employed as a PET computer scientist & mathematician at the Dept. of Clincical Physiology, Nuclear Medicine and PET, working in molecular imaging.
My research focus areas are:
Algorithms and software development for PET imaging.
Motion tracking and correction in PET brain imaging.
Research on the Siemens mMR simultaneous PET/MR scanner; attenuation correction, motion correction, PET quantification.
While at DIKU I worked on using variational methods
for video upscaling, that is increasing the resolution by deinterlacing, spatial super resolution
(e.g SDTV to HDTV) or super resolution in time (higher frame rate or super slow). Variational methods are
widely used for image restorations, e.g. de-noising and inpainting and motion estimation.
Publications
A fully updated publication list can be found at Google Scholar.
2014
Sune H. Keller, Adam E. Hansen, Søren Holm, Thomas Beyer. Image Distortions in Clinical PET/MR Imaging. In PET/MRI (Carrio I, Ros P; Editors), Jan 2014, p. 21-41, Springer, ISBN 978-3-642-40691-1.
Claes Nøhr Ladefoged, Adam Espe Hansen, Sune Høgild Keller, Søren Holm, Ian Law, Thomas Beyer, Liselotte Højgaard, Andreas Kjær and Flemming Littrup Andersen. Impact of incorrect tissue classification in Dixon-based MR-AC: fat-water tissue inversion.EJNMMI Physics 1:101, 2014.
Flemming Littrup Andersen, Claes Nøhr Ladefoged, Thomas Beyer, Sune Høgild Keller, Adam Espe Hansen, Liselotte Højgaard, Andreas Kjær, Ian Law and Søren Holm. Combined PET/MR imaging in neurology: MR-based attenuation correction implies a strong spatial bias when ignoring bone.NeuroImage, 84, pp. 206-216, Jan. 2014.
A. Knudsen, A. M. Hag, A. Loft, E. von Benzon, S. H. Keller, H. J. Møller, A. M. Lebech, R. S. Ripa and A. Kjær. HIV-infection and arterial inflammation assessed by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET): A prospective cross-sectional study.Journal of Nuclear Cardiology, Epub, Dec. 2014.
C. N. Ladefoged, F. L. Andersen, S. H. Keller, T. Beyer, L. Højgaard, F. Lauze. Correction of dental artifacts within the anatomical surface in PET/MRI using active shape models and k-nearest-neighbors. Proceedings of SPIE Medical Imaging, 2014.
IEEE NSS/MIC 2014:
Sune H. Keller, Claus Svarer and Merence Sibomana
Validation of Scatter Simulation in 3D and Count-Rate Dependent Component-Based Normalization for the HRRT . IEEE Nuclear Science Symposium & Medical Imaging Conference Record, IEEE, 2014.
Charles C. Watson, Vladimir Y. Panin, Sune H. Keller, Søren Holm and Johan Nuyts. A Sparse Transmission Method for PET Attenuation
Correction in the Head. IEEE Nuclear Science Symposium & Medical Imaging Conference Record, IEEE, 2014.
D. Benoit, C. N. Ladefoged, A. Rezaei, S. H. Keller, F. L. Andersen, L. Højgaard, A. E. Hansen, S. Holm and J. Nuyts.Simultaneous Reconstruction of Activity and Attenuation Using UTE Mu-Maps and T1-Weighted MR Images for PET/MR Brain Imaging. IEEE Nuclear Science Symposium & Medical Imaging Conference Record, IEEE, 2014.
Selected Abstract:
Sune H. Keller, Casper Hansen, Christian Hansen, Flemming L. Andersen, Claes Ladefoged, Claus Svarer, Andreas Kjær, Liselotte Højgaard, Ian Law, Otto M. Henriksen, Adam E. Hansen Motion Correction in Simultaneous PET/MR Brain Imaging Using Sparsely Sampled MR Navigators EJNMMI 41, Sxxx, 2014. Included in 'Highlights of EANM 2014'.
Sune H. Keller, Søren Holm, Adam E. Hansen, Bernhard Sattler, Flemming Andersen, Thomas L. Klausen, Liselotte Højgaard, Andreas Kjær and Thomas Beyer
Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI,
Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA), DOI 10.1007/s10334-012-0345-4, vol. 26, issue 1, pp. 173-81, Feb. 2013.
Andreas Kjær, Annika Loft, Ian Law, Anne Kiil Berthelsen, Lise Borgwardt, Johan Löfgren, Camilla B. Johnbeck, Adam E. Hansen, Sune Keller, Søren Holm and Liselotte Højgaard
PET/MRI in cancer patients: first experiences and vision from Copenhagen,
Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA) vol. 26, issue 1, pp. 37-47, Feb. 2013.
Claes Nøhr Ladefoged, Flemming Littrup Andersen, Sune Høgild Keller, Johan Löfgren, Adam Espe Hansen, Søren Holm, Liselotte Højgaard and Thomas Beyer
PET/MR imaging of the pelvis in the presence of endoprostheses: reducing image artifacts and increasing accuracy through inpainting,
Eur J Nucl Med Mol Imaging, DOI 10.1007/s00259-012-2316-4, 2013.
Olesen OV, Paulsen RR, Jensen RR, Keller SH, Sibomana M, Højgaard L, Roed B, Larsen R. 3D Surface Realignment Tracking for Medical Imaging: A Phantom Study with PET Motion Correction. In Image-Based Geometric Modeling and Mesh Generation (Zhang Y, Ed.), Springer Netherlands, Jan 2013, p. 11-19, ISBN 978-94-007-4254-3.
Rasmus S Ripa, Andreas Knudsen, Anne Mette F Hag, Anne-Mette Lebech, Annika Loft, Sune H Keller, Adam E Hansen, Eric von Benzon, Liselotte Højgaard, Andreas Kjær. Feasibility of simultaneous PET/MR of the carotid artery: first clinical experience and comparison to PET/CT. American journal of nuclear medicine and molecular imaging 2013;3(4):361-71.
IEEE NSS/MIC 2013:
Reader AJ, Tahaei MS, Rahmim A, Keller SH, Blinder S, Sibomana M, Soucy JP. Multi-Centre Assessment of HRRT Image Uniformity via 68 Ge and 18 F Cylindrical and Anthropomorphic Phantoms. IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, 2013.
C. N. Ladefoged, F. L. Andersen, T. Beyer, A. E. Hansen, S. H. Keller, I. Law, L. Hoejgaard, A. Kjaer, F. Lauze.PET/MR Imaging of the Head/neck: Automatic Correction of Dental Implant Artifacts Exceeding Anatomical Surfaces. . IEEE Nuclear Science Symposium (MIC), IEEE, 2013.
Abstract, EJR 2013:
Claes Nøhr Ladefoged, Flemming Andersen, Sune H. Keller, Johan Löfgren, Adam Espe Hansen, Søren Holm, Liselotte Højgaard and Thomas Beyer
PET/MR imaging of the pelvis in the presence of endoprostheses: reducing image artifacts and increasing accuracy through inpainting,
ECR 2013, Wien (Vienna), March 2013.
Abstract, PSMR 2013:
FL Andersen, C Ladefoged, T Beyer, S H Keller, A E Hansen, L Højgaard, I Law and S Holm. Combined PET/MR brain imaging: a spatially dependent bias in PET activity results if bone attenuation is not accounted for. PSMR, Aachen, May 2013.
Abstracts, SNM 2013:
Rasmus Ripa, Andreas Knudsen, Anne Mette Hag, Anne Mette Lebech, Annika Loft, Sune Keller, Adam Hansen, Eric von Benzon, Liselotte Højgaard, Andreas Kjær. Feasibility of simultaneous PET/MR of the carotid artery: First clinical experience and comparison to PET/CT.
Karin Stahr, Jákup Martin Poulsen, Marianne Federspiel, Adam Hansen, Sune Keller, Liselotte Højgaard, Thomas Beyer. Patient comfort and compliance in combined PET/MR imaging.
Abstracts, EANM 2013:
I Law, FL Andersen, T Beyer, AE Hansen, M Lundemann, C Ladefoged, SH Keller, S Holm, L Højgaard. The effects of MR-based attenuation correction on the evaluation of gliomas using [18F]-FET PET/MRI. EJNMMI 40, S238, 2013.
CN Ladefoged, T Beyer, SH Keller, I Law, L Hojgaard, A Kjaer, F Lauze, FL Andersen. PET/MR imaging of head/neck in the presence of dental implants: reducing image artifacts and increasing accuracy through inpainting. EJNMMI 40, S228, 2013.
K Stahr, J Poulsen, M Federspiel, A Hansen, SH Keller, HH Johannesen, T Beyer, J Löfgren. A multi-disciplinary approach to the education and operative responsibilities ensures an efficient adoption of PET/MR in clinical routine. EJNMMI 40, S524, 2013.
Quantification and accuracy of clinical [11C]-PiB PET/MRI: The effect of MR-based attenuation correction. I Law, FL Andersen, T Beyer, AE Hansen, S Hasselbalch, C Ladefoged, SH Keller, S Holm, L Højgaard. EJNMMI 40, S143, 2013.
Thomas Levin Klausen, Sune Høgild Keller, Oline Vinter Olesen, Marianne Aznar and Flemming L. Andersen
Innovations in PET/CT,
The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2012, 56(3):268-79, 2012.
Sune H. Keller, Adam E. Hansen, Thomas Beyer, Flemming L. Andersen, Thomas L. Klausen, Johan Löfgren, Søren Holm
Evaluation of PET Image Quality and Distortions in Simultaneous Clinical PET/MR,
IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, 2012.
Merence Sibomana, Sune H. Keller, Simon Stute, Claude Comtat
Benefits of 3D Scatter Correction for the HRRT - a Large Axial FOV PET Scanner,
IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, 2012.
Abstracts:
Sune H. Keller, Thomas Beyer, Thoams L. Klausen, Flemming L. Andersen, Ian Law, Annika Loft, Søren Holm and Liselotte Højggaard
Evaluation of PET image distortions in clinical PET/MR,
PSMR 2012, Elba, Italy, Online.
F. L. Andersen, S. H. Keller, A. E. Hansen, T. Beyer, I. Law, L. Højgaard, S. Holm
Bone attenuation in brain-PET/MR imaging should be accounted for during attenuation correction and PET reconstruction,
EANM '12, Milano, 2012.
T. Beyer, S. Keller, A. Hansen, A. Loft, J. Löfgren, L. Hojgaard, S. Holm
Metal implants appear to be less detrimental to the PET quality in PET/MR than in PET/CT imaging,
EANM '12, Milano, 2012.
J. Löfgren, A. Loft, A. K. Berthelsen, A. E. Hansen, S. H. Keller, S. Holm, L. Højgaard, T. Beyer
Validation of FDG-PET/MR imaging in gynecological cancer compared to standard clinical FDG-PET/CT,
EANM '12, Milano, 2012.
A. Loft, A. K. Berthelsen, A. E. Hansen, S. H. Keller, J. Löfgren, F. L. Andersen, T. L. Klausen, L. Hojgaard, T. Beyer
Are PET volumes from PET/MR equal to PET volumes from PET/CT?,
EANM '12, Milano, 2012.
Søren Holm, Thomas Beyer, Adam Hansen, Sune H. Keller, Ian Law, Annika Loft, Johan Löfgren, Liselotte Højgaard
Image quality in clinical PET/MR: MLAA effectively removes truncation artifacts,
RSNA Annual Meeting, Chicago, 2012.
Karine Madsen, Mette T. Haahr, Lisbeth Marner, Sune H. Keller, William F. Baaré, Claus Svarer, Steen G. Hasselbalch, Gitte M. Knudsen:
Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study,
Journal of Cerebral Blood Flow & Metabolism, 2011;31(6):1475-81.
Oline V. Olesen, Rasmus R. Paulsen, Rasmus R. Jensen, Sune H. Keller, Merence Sibomana, Liselotte Højgaard, Bjarne Roed, and Rasmus Larsen:
3D Surface Realignment Tracking for Medical Imaging: A Phantom Study with PET Motion Correction,
In Proceedings of the MICCAI workshop on Mesh Processing in Medical Image Analysis (MeshMed), Ed. Yongjie Zhang, Springer, 2011. (Accepted for publication.)
Olesen V. Olesen, Rasmus R. Paulsen, Sune H. Keller, Liselotte Højgaard, Bjarne Roed, and Rasmus Larsen:
Comparison of external motion tracking systems for PET list-mode reconstruction, In
IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, 2011.
Oline Vinter Olesen, Claus Svarer, Merence Sibomana, Sune Høgild Keller, Søren Holm, Jørgen A. Jensen, Flemming Andersen and Liselotte Højgaard:
A Movable Phantom Design for Quantitative Evaluation of Motion Correction Studies on High Resolution PET Scanners, In
IEEE Trans. on Nuclear Science, Vol. 57, Issue 3. pp. 1116 - 1124, June 2010.
M. C. Huisman, J. E. M. Mourik, F. H. P. van Velden, M. Sibomana, S. H. Keller, S. Wang, J. Anton, D. van Assema,
F. E. A. M. Froklage, N. J. Hoetjes, R. W. Kloet, B. N. M. van Berckel, R. C. Schuit, M. Lubberink, R. Boellaard, A. A. Lammertsma
Quantitative Accuracy of the HRRT in an Interscanner Study with the HR+ and (R)-[11C]verapamil,
2010 IEEE Nuclear Science Symposium (MIC), IEEE, 2010.
Merence Sibomana, Sune Høgild Keller, Søren Holm, Peter M. Bloomfield, Stephan Blinder, Søren Baarsgaard Hansen and Christian Michel
Component-Based Normalization for the HRRT Sinogram-Mode Reconstruction,
In 2009 IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, 2009.
2008
Sune Høgild Keller, François Lauze and Mads Nielsen: Deinterlacing Using Variational Methods, In
IEEE Transactions on Image Processing, volume 17, number 11, pages 2015-2028, ieeexplore.ieee.org, 2008.
Video examples referenced in the paper can be found here.
2007
Sune Høgild Keller, François Lauze and Mads Nielsen: Motion Compensated Video Super Resolution, In
F. Sgallari, A. Murli and N. Paragios, editors,
Scale Space and Variational Methods in Computer Vision, SSVM 2007 Proceedings, LNCS 4485, pages 801-812, Berlin, Springer, 2007.
Video examples referenced in the paper can be found here.
2006
Sune Keller, François Lauze and Mads Nielsen: Variational Motion Compensated Deinterlacing, In: 3rd Workshop on
Statistical Methods in Multi-Image and Video Processing (SMVP), 9th ECCV Workshop Proceedings, 2006.
Sune Høgild Keller, François Lauze and Mads Nielsen: Variational Deinterlacing, IT University Technical
Report Series, TR-2006-90, ISBN 87-7949-134-0, 2006.
2005
Sune Keller, François Lauze and Mads Nielsen: A Total Variation Motion Adaptive Deinterlacing Scheme,
In: R. Kimmel, N. Sochen and J. Weickert, editors, Scale Space and PDE Methods in Computer Vision, 5th International Conference,
Scale-Space 2005, Proceedings, LNCS 3459, pages 408-419, Berlin, Springer, 2005.
30/09/2004: US 60/614,420, A Method of Adding Information to a Frame or a Field in a Video Sequence, Inventors: Sune Keller,
François Lauze and Mads Nielsen.
30/09/2005: PCT WO-A-2006/035072 (PCT/EP2005/054957), A Method of Adding Information to a Frame or a Field in a Video Sequence,
Inventors: François Lauze, Sune Keller and Mads Nielsen.
30/09/2005: US 11/239697, A Method of Adding Information to a Frame or a Field in a Video Sequence,
Inventors: François Lauze, Sune Keller and Mads Nielsen.
Education
B.Sc. in Chemistry with a second major in Film and Media Science, Copenhagen University, June 2001.
M.Sc. in IT, Multimedia Technology, IT University of Copenhagen, June 2004.
Ph.D. from The Image Group, Department of Computer Science, Faculty of Science, University of Copenhagen, December 2007.
